Alexey Anatolievitch Agranovsky, educated from the high school in 1970.
Professional experience:
In 1970-1975 graduated as a diploma in plant biochemistry from the Department of Plant Biochemistry, Faculty of Biology, Moscow State University.
1975-1977, Researcher Probationer, Department of Virology, Faculty of Biology, Moscow State University. 1977-1983, Senior Laboratory Assistant, the same Department. In 1981, received the Ph.D. (Candidate of Biological Sciences) at the Department of Virology of the same Faculty, for the Thesis on "The study on peculiarities of terminal structures in barley stripe mosaic virus RNA". 1983-1984, Junior Research Officer, the same Department.
1984-1987, Senior Research Officer, Head of the Virology Department of the Scientific Phytopathological Laboratory (USSR Ministry of Agriculture) in Ethiopia; also Editor-in-Chief of the "Ethiopian Phytopathological Committee (EPC) Newsletter" (1985-1986), and a guest lecturer on plant virology at the Addis Ababa University.
1987-1989, Research Officer, Department of Plant Virus Biochemistry, A.N.Belozersky Laboratory, Moscow State University. 1989-1991, Senior Research Officer at the same Department.
1991-1993, visiting scientist on leave from Moscow State University at the Federal Biological Research Center for Agriculture and Forestry (Biologische Bundesanstaly fuer Land- und Forstwirtschaft) at Braunschweig, Germany (research fellowship fom the Alexander von Humboldt Foundation).
From September, 1993, returns to work in Russia as a Senior Research Officer at the Department of Plant Virus Biochemistry, A.N.Belozersky Institute at Moscow State University.
1996 until present, Head of the Virus Molecular Biology Sector, Department of Virology, Moscow University.
Doctor of Sciences (1994), Professor of Moscow University (2004), Laureate of the Leninski Komsomol Prize in Science and Technology (1981).
Personal status:
Born June 23, 1953, in Moscow.
Married, has one child.
1. Agranovsky, A.A., Dolja, V.V., Kavsan, V.M., and Atabekov, J.G. (1978). Detection of polyadenylate sequences in RNA components of barley stripe mosaic virus (BSMV). Virology 91, 95-105.
2. Agranovsky, A.A., Dolja, V.V., Kagramanova, V.K., and Atabekov, J.G. (1979). The presence of a cap structure at the 5'-end of BSMV RNA. Virology 95, 208-210.
3. Negruk, V.I., Agranovsky, A.A., Skryabin, K.G., and Atabekov, J.G. (1979). Size determination of poly(A) sequences in barley stripe mosaic virus RNA. Analytical Biochemistry 99, 450-453.
4. Agranovsky, A.A., Dolja, V.V., Gorbulev, V.G., Kozlov, Y.V., and Atabekov, J.G. (1981). Aminoacylation of barley stripe mosaic virus RNA: polyadenylate-containing RNA has a 3'-terminal tyrosine-accepting structure. Virology 113, 174-187.
5. Аграновский, А.А., Доля, В.В. и Атабеков, И.Г. (1981). Аминоацилирование компонентов вирионной РНК вируса штриховатой мозаики ячменя. Биологические Науки 16, 160-169.
6. Морозов, С.Ю., Горбулев, В.Г., Новиков, В.К., Аграновский, А.А., Козлов, Ю.В., Атабеков, И.Г. и Баев, A.A. (1981). Первичная структура 5'- и 3'-концевых районов РНК Х-вируса картофеля. Доклады Академии Наук СССР 259, 723-725.
7. Agranovsky, A.A., Dolja, V.V., and Atabekov, J.G. (1982). Structure of the 3'-extremity of barley stripe mosaic virus RNA: evidence for internal poly(A) and a 3'-terminal tRNA-like structure. Virology 119, 51-58.
8. Taliansky, M.E., Kaplan, I.B., Yarvekulg, L.V., Atabekova, T.I., Agranovsky, A.A, and Atabekov, J.G. (1982). A study of TMV ts-mutant Ni2519.
V. Temperature- sensitive behavior of Ni2519 RNA upon reassembly. Virology 118, 309-316.
9. Каплан, И.Б., Тальянский, М.Э., Аграновский, А.А. и Атабеков, И.Г. (1982). Локализация сайтов инициации реконстукции в молекуле РНК мутанта ВТМ Ni2519. Молекулярная Биология 16, 160-169.
10. Dolja, V.V., Agranovsky, A.A., Lunina, N.A., and Atabekov, J.G. (1983). Short virion RNA in barley stripe mosaic virus. FEBS Letters 151, 215-218.
11. Agranovsky, A.A., Dolja, V.V., and Atabekov, J.G. (1983). Differences in polyadenylate length between individual barley stripe mosaic virus RNA species. Virology 129, 344-349.
12. Kozlov, Y.V., Rupasov, V.V., Adyshev, V.D., Belgelarskaya, S.N., Agranovsky, A.A., Mankin, A.S., Morozov, S.Y., Dolja, V.V., and Atabekov, J.G. (1984). Nucleotide sequence of the 3'-terminal tRNA-like structure in barley stripe mosaic virus genome. Nucleic Acids Research 12, 4001-4009.
13. Доля, В.В. и Аграновский, А.А. (1984). Структура генома гордеивирусов. Успехи Биологической Химии 25, 140-145.
14. Agranovsky, A.A., Dolja, V.V., and Atabekov, J.G. (1986). Poly(A) content in RNA of the progeny of poly(A) and poly(A) RNA of barley stripe mosaic virus. Arch. Phytopathol. und Pflanzenshutz (Berlin) 22, 435-440.
15. Agranovsky, A.A., and Bedasso Jabessa (1985). Identification of two potyviruses infecting pepper and onion in Ambo region. Ethiopian Phytopathological Committee Newsletter 22, 6-9.
16. Agranovsky, A.A., and Mitiku Tesso (1986). Further characterization of some virus isolates infecting peppers in Ethiopia. Ethiopian Phytopathological Committee Newsletter 30, 9-19.
17. Agranovsky, A.A., and Bedasso Jabessa (1986). Identification of viruses infecting haricot bean and soybean. Scientific Phytopathological Laboratory Progress Report for 1985/86, pp. 177-180, 200-212.
18. Agranovsky, A.A., and Anisimov, B.V. (1986). Virus diseases of tomato in Ethiopia. Acta Horticulturae 190, 115-119.
19. Karasev, A.V., Agranovsky, A.A., Rogov, V.V., Miroshnichenko, N.A., Dolja, V.V., and Atabekov, J.G. (1989). Virion RNA of beet yellows closterovirus, cell-free translation and some properties. Journal of General Virology 70, 241-245.
20. Dolja, V.V., Karasev, A.V., and Agranovsky, A.A. (1990). Organization of beet yellows closterovirus genome. In New Aspects of Positive-Strand RNA Viruses, pp. 31-35, edited by M.Brinton and F.Heinz. Washigton, D.C., American Society for Microbiology.
21. Agranovsky, A.A., Boyko, V.P., Karasev, A.V., Lunina, N.A., Koonin, E.V., and Dolja, V.V. (1991). Nucleotide sequence of the 3'-terminal half of beet yellows closterovirus RNA genome: unique arrangement of eight virus genes. Journal of General Virology 72, 15-23.
22. Agranovsky, A.A., Boyko, V.P., Karasev, A.V., Koonin, E.V., and Dolja, V.V. (1991). The putative 65K protein of beet yellows closterovirus is a homologue of HSP70 heat shock proteins. Journal of Molecular Biology 217, 603-610.
23. Dolja, V.V., Boyko, V.P., Agranovsky, A.A., and Koonin, E.V. (1991). Phylogeny of capsid proteins of rod-shaped and filamentous RNA plant viruses: two families with distinct patterns of sequence and probably structure conservation. Virology 184, 79-86.
24. Agranovsky, A.A. (1992). Exogenous primer-independent cDNA synthesis with commercial reverse transcriptase preparations on plant virus RNA templates. Analytical Biochemistry 203, 163-165.
25. Agranovsky, A.A., Karasev, A.V., Novikov, V.K., Lunina, N.A., Loginov, S., and Tyulkina, L.G. (1992). Poa semilatent virus, a hordeivirus having no internal polydisperse poly(A) in the 3' non-coding region of the RNA genome. Journal of General Virology 73, 2085-2092.
26. Boyko, V.P., Karasev, A.V., Agranovsky, A.A., Koonin, E.V., and Dolja, V.V. (1992). Coat protein gene duplication in a filamentous RNA virus of plants. Proc. Natl. Acad. Sci. USA 89, 9156-9160.
27. Rogov, V.V., Karasev, A.A., and Agranovsky, A.A. (1993). Purification and some properties of an isolate of beet yellows virus from Ukraine. Journal of Phytopathology 137, 79-88.
28. Agranovsky, A.A. (1993). Virus diseases of pepper (Capsicum annum L.) in Ethiopia. Journal of Phytopathology 138, 89-97.
29. Agranovsky, A.A., Koonin, E.V., Boyko, V.P., Maiss, E., Froetschl, R., Lunina, and Atabekov, J.G. (1994). Beet yellows closterovirus: complete genome structure and identification of a leader papain-like thiol protease. Virology 198, 311-324.
30. Agranovsky, A.A., Koenig, R., Maiss, E., Boyko, V.P., Casper, R., and Atabekov, J.G. (1994). Expression of the beet yellows closterovirus capsid protein and p24, a capsid protein homologue, in vitro and in vivo. Journal of General Virology 75, 1431-1439.
31. Dorokhov, Yu.L., Ivanov, P.A., Novikov, V.K., Agranovsky, A.A., Morozov, S.Yu., Efimov, V.A., Casper, R., and Atabekov, J.G. (1994). Complete nucleotide sequence and genome organization of a tobamovirus infecting cruciferae plants. FEBS Letters 350, 5-8.
32. Никифорова, С.Ю., Аграновский, А.А. и Атабеков, И.Г. (1995). Экспрессия в бактериях и некоторые свойства р65, гомолога клеточных белков теплового шока HSP70, закодированного в РНК геноме клостеровируса желтухи свеклы. Доклады Академии Наук 340, 416-418.
29. Agranovsky, A.A., Koonin, E.V., Boyko, V.P., Maiss, E., Froetschl, R., Lunina, and Atabekov, J.G. (1994). Beet yellows closterovirus: complete genome structure and identification of a leader papain-like thiol protease. Virology 198, 311-324.
33. Agranovsky, A.A., Lesemann, D.E., Maiss, E., Hull, R. and Atabekov, J.G.(1995). "Rattlesnake" structure of a filamentous plant RNA virus built of two capsid proteins. Proc. Natl. Acad. Sci. USA 92, 2470-2473.
34. Аграновский, А.А. (1995). Структура и экспрессия РНК геномов клостеровирусов. Мол. Биология 29, No6, 1265-1285 (Mol. Biol. 29, 751-764).
35. Agranovsky, A.A. (1996). Principles of molecular organization, expression and evolution of closteroviruses: Over the barriers. Adv. Virus Res. 47, 119-158.
36. Solovyev, A.G., Savenkov, E.I., Agranovsky, A.A., and Morozov, S.Yu. (1996). Comparisons of the genomic cis-elements and coding regions in RNAb components of the hordeiviruses barley stripe mosaic virus, lychnis ringspot virus, and poa semilatent virus. Virology 219, 9-18.
37. Agranovsky, A.A., Folimonova, S.Yu., Folimonov, A.S., Denisenko, O.N., and Zinovkin, R.A. (1997). The beet yellows closterovirus p65 homologue of HSP70 chaperones has ATPase activity associated with its conserved N-terminal domain but does not interact with unfolded protein chains. J. Gen. Virol. 78, 535-542.
38. Vitushkina, M.V., Fetchner, B., Agranovsky, A. A., and Jelkmann, W. (1997). Development of an RT-PCR for the detection of little cherry virus and characterization of some isolates occurring in Europe. Eur. J. Plant. Pathol. 103, 803-808.
39. Jelkmann, W., Fetchner, B., and Agranovsky, A. A. (1997). Complete genome structure and phylogenetic analysis of little cherry virus, a mealybug-transmissible closterovirus. J. Gen. Virol. 78, 2067-2071.
40. Agranovsky, A.A. (1998). Closterovirus papain-like cysteine endopeptidases. In Handbook of Proteolytic Enzymes (A.J. Barrett, N.D. Rawlings and J.F. Woessner, eds), chapter 237, pp. 700-702, Academic Press, New York.
41. Agranovsky, A. A., Folimonov, A. S., Folimonova, S. Yu., Morozov, S. Yu., Schiemann, J., Lesemann, D.E., and Atabekov, J. G. (1998). Beet yellows closterovirus HSP70-like protein mediates the cell-to-cell movement of a potexvirus transport-deficient mutant and a hordeivirus-based chimeric virus. J. Gen. Virol. 79, 889-895.
42. Зиновкин, Р. А. и Аграновский, А. А. (1998). Обнаружение неструктурного белка р21 клостеровируса желтухи свеклы in vivo с помощью поликлональных антител к белку, экспрессированному в бактериях. Мол. Биол. 32, No 6, 1095-1098.
43. Фолимонова, C.Ю., Фолимонов, А.С., Аграновский, А.А. и Атабеков, И.Г. (1998). Идентификация штамма Y-вируса картофеля, вызывающего кольцевой некроз клубней (YВК-NTN), c помощью иммуноспецифической полимеразной цепной реакции (ИС-ПЦР). Вестник РАСХН No 5, 16-18.
44. Agranovsky, A.A., and Morozov, S. Yu. (1999). Gene expression in positive strand RNA viruses. In Molecular Biology of Plant Viruses (C.L. Mandahar, ed.), chapter 4, pp. 99-119, Kluwer Academic Publishers:Boston.
45. Zinovkin, R.A., Jelkmann, W., and Agranovsky, A.A. (1999). The minor coat protein of beet yellows closterovirus encapsidates the 5’-terminus of RNA in virions. J. Gen. Virol. 80, 269-272.
46. Atabekov, J.G. , Malyshenko, S.I., Morozov, S.Yu., Taliansky, M.E., Solovyev, A.G., Agranovsky, A.A., and Shapka N.A. (1999). Identification and study of tobacco mosaic virus movement function by complementation tests. Phil. Trans. R. Soc. Lond. B 354, 629-635.
47. Фолимонова, C.Ю., Приходько, Ю.Н., Аграновский, А.А. и Атабеков, И.Г. (1999). Идентификация вирусов бороздчатости ствола яблони (ASGV) и ямчатости ствола яблони (ASPV) c помощью иммуноспецифической полимеразной цепной реакции (ИС-ПЦР). Вестник РАСХН No 1, 13-14.
48. Agranovsky, A.A., and Lesemann, D.E. (2000). Beet yellows virus. CMI/AAB Descriptions of Plant Viruses No 377 (http://www.dpvweb.net/dpv/showdpv.php?dpvno=377).
49. Erokhina, T.N., Zinovkin, R.A., Vitushkina, M.V., Jelkmann, W., and Agranovsky, A.A. (2000). Detection of beet yellows closterovirus methyltransferase-like and helicase-like proteins in vivo using monoclonal antibodies. J. Gen. Virol. 81, 597-603.
50. Erokhina, T.N., Vitushkina, M.V., Zinovkin, R.A., Lesemann, D.E., Jelkmann, W., Koonin, E.V., and Agranovsky, A.A. (2001). Ultrastructural localisation and epitope mapping of beet yellows closterovirus methyltransferase-like and helicase-like proteins. J. Gen. Virol. 82, 1983-1994.
51. Zamyatnin, A.A., Solovyev, A.G., Sablina, A.A., Agranovsky, A.A., Katul, L., Vetten, H.J., Schiemann, J., Hinkkanen, A.E., Lehto, K .& Morozov, S.Y. (2002). Dual-colour imaging of membrane protein targeting directed by poa semilatent virus movement protein TGBp3 in plant and mammalian cells. J. Gen. Virol. 83, 651-662.
52. Agranovsky, A.A. & Lesemann, D.E. (2002). Closterovirus. In: The Springer Index of Viruses (C.A. Tidona & G. Darai, eds.). Springer-Verlag: Berlin, Heidelberg, New York, pp. 236-243.
53. Martelli, G.P., Agranovsky, A.A., Bar-Joseph, M., Boscia, D., Candresse, T., Coutts, R.H.A., Dolja, V.V., Falk, B.W., Gonsalves, D., Jelkmann, W., Karasev, A.V., Minafra, A., Namba, S., Vetten, H.J., Wisler, G.C., Yoshikawa, N. (2002). The family Closteroviridae revised. Arch. Virology 147, 2039-2044.
54. Zinovkin, R.A., Erokhina, T.N., Lesemann, D.E., Jelkmann, W. & Agranovsky, A.A. (2003). Processing and subcellular localization of the leader papain-like proteinase of beet yellows closterovirus. J. Gen. Virol. 84, 2265-2270.
55. Agranovsky, A.A. (2004). Closterovirus papain-like cysteine proteinases. In Handbook of Proteolytic Enzymes, 2nd Edn (A.J. Barrett, N.D. Rawlings and J.F. Woessner, eds), chapter 400, pp.1285-1287, Academic Press, New York.
56. Тилькунова, Т. Ю., Зиновкин, Р.А., и Аграновский, А. А. (2004). РНК-связывающие свойства белков клостеровируса желтухи свеклы. Молекулярная биология 38, 553-558.
